APIs

Lercanidipine hydrochloride

Common Name：Lercanidipine hydrochloride
CAS Number：132866-11-6
Molecular Weight：648.188
Boiling Point：712.5ºC at 760mmHg
Molecular Formula：C36H42ClN3O6
Melting Point：175-177ºC
Flash Point ：384.7ºC
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Product Details：

Product Description:

Product Name: Lercanidipine hydrochloride

CAS NO: 132866-11-6

Synonyms:

Renovia

Vasodip

Carmen

Lercadip

Lercan

Lercaton

2-((3,3-diphenylpropyl)methylamino)-1,1-dimethylethyl methyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate monohydrochloride

Lercapin

Lerdip

Cardiovasc

Lercanidipine hydrochloride

Corifeo

Lercanidipine hydrochloride hemihydrate

Lerkamen

Zanicor

1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride (1:1)

Masnidipine hydrochloride

REC 15-2375

1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)

Lerzam

MFCD07773089

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, hydrochloride (1:1)

Zandip

Zanidip

Lercanidipine (hydrochloride)

Sepcs:

Product Name	Lercanidipine hydrochloride
CAS. No.	132866-11-6	Batch No.	20220403
Date of Manufacture	2022-04-03	Quantity	125kgs
Date of Retest	2025-04-02	Analysis Date	2022-04-08
Test Items	Specifications	Results
Appearance	Light yellow or yellow powder	Light yellow powder
Identification	Conforms to standard infrared spectrum	Conforms
Loss on drying	Not more than 1.0%	0.45%
Residue on ignition	Not more than 0.5%	0.08%
Heavy metal	Not more than 10 ppm	Conform
Related substances (By HPLC)
Single impurity	Not more than 0.1%	0.04%
Total impurities	Not more than 1.0%	0.60%
Assay (By HPLC)	Not less than 99.0%	99.40%
Conclusion	The test product conform to the requirements of Enterprise Standard.
Storage condition	Room temperature, in a closed container.

Chemical & Physical Properties:

Boiling Point: 712.5ºC at 760mmHg

Melting Point: 175-177ºC

Molecular Formula: C36H42ClN3O6

Molecular Weight: 648.188

Flash Point: 384.7ºC

Exact Mass: 647.276184

PSA: 113.69000

LogP: 8.13240

Vapour Pressure: 3.77E-20mmHg at 25°C

Use of Lercanidipine hydrochloride:

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.Target: Calcium ChannelLercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk.

Storage: Stored in a dry well-closed container. Keep away from moisture and strong light/heat.

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